According to the 1915 History of Clinton County, Johanna Creedon Keefe and her husband John Keefe came to Clinton County, Ohio in 1858. Their son Timothy Keefe was married to Bridget Dowling in 1872 in Clinton County. Timothy lost his mother and wife within two weeks of each other in 1892.
The Keefe family lived close to my Creeden family in Clinton County, so I've wondered if Johanna was related to them. Both families have probable ties to Clondrohid parish in County Cork, Ireland, so it looks like a good possibility.
From the Cemetery Records of Clinton County, Ohio, 1798-1978, Johanna is buried in Section 4, Lot 27 in Sugar Grove Cemetery. She was born in Ireland and died on 1-1-1892 at the age of 88. That would place her birth year around 1803. The entry says she was the widow of Timothy Keefe. I think this is a mistake in the entry and it should read the "mother" of Timothy Keefe. Bridget is also buried in Section 4, Lot 27 and there is a note in the entry saying "Kin Patrick Regan, cousin".